Oncology and Immuno-oncology Drug Development
Crown Bioscience: A Global Leader in Preclinical CRO Services
Crown Bioscience is one of the major global Contract Research Organization with expertise in discovery, preclinical and translational science. Headquartered in San Diego, USA, Crown Bioscience has operations in 10 global locations spread across US, Europe and Asia. They are the only preclinical CRO to provide tumor organoid services utilizing HUB technology and has the world’s largest commercially available PDX collection, helping deliver superior drug candidates to ensure that patients get the right treatment at the right time.
As an authorized distributor for Crown Bioscience in India, GVRP brings their expertise in the areas of oncology, immuno-oncology and towards accelerating Indian biomedical research programs using the comprehensive suite of In-silico, in-vitro & in-vivo biological services.
In Vitro Platform
Indivumed Services, a Crown Bioscience company, offers a leading oncology and immuno-oncology in vitro biology platform . This platform is de signed to support the pharmacological characterization of lead compounds, helping companies save time and resources.
Access the following cutting-edge solutions :
- 2D Cell Lines and Panels: Focused panels featuring relevant cell lines.
- 2D HuCell™: Mouse tumor cells engineered to express humanized targets.
- CRISPR/Cas9: Precise and efficient cell DNA editing.
- Organoids: Advanced 3D organoids providing unparalleled predictivity of patient responses.
Crown Bioscience offers tailored study designs and screening methods using a suite of validated in vivo models.
Gain access to these specialized platforms :
- PDX Models:Indication-specific models across diverse databases.
- CDX Models:Comprehensive databases of well-characterized cell lines, including standard-of-care and RNAseq data, to simplify model selection.
- Syngeneic Models:Simplified models for evaluating single-agent and combination immunotherapies.
- Humanized HSC-PDX Models:Tailored for human-specific immunotherapy evaluation.
- Orthotopic Models with Advanced Imaging:Superior preclinical predictivity compared to subcutaneous alternatives.
Crown Bioscience’s integrated solutions ensure precise and predictive data to accelerate drug development and enhance patient outcomes.
