Step into the forefront of scientific advancement with humanized mice models, where innovation meets preclinical research. Biocytogen pioneers this field, offering meticulously designed models that transcend boundaries and propel research across various fields.
With a commitment to reliability and precision, these models serve as invaluable tools for evaluating drug candidates, from cancer therapy to infectious diseases and beyond.
Explore the endless possibilities of preclinical research with Biocytogen’s humanized mice models, shaping the future of biomedical science.
Humanized Immune-Checkpoint Mice
checkpoint therapy has emerged as a paradigm-shifting approach, capable of restoring immune function by blocking inhibitory checkpoints or activating stimulatory molecules. In recent years, immune-checkpoint drugs have reshaped cancer treatment paradigms, paralleled by advancements in immuno-oncology mouse models.
Key Features of Biocytogen’s Humanized Immune-Checkpoint Mice:
- Pure C57BL/6 genetic background ensures consistency and reliability in experimental outcomes.
- Developed using the commonly employed C57BL/6 genetic background, ideal for oncology, physiology, immunology, and genetics studies.
- Meticulously designed and generated humanized mice maintain biological functionality, enhancing the reliability of drug validation.
- Experts consider all potential factors affecting humanized protein expression, devising detailed, scientifically accurate plans for optimal humanization.
- Rigorous planning ensures sufficient humanization, humanized protein expression, and unimpeded signal transduction.
Click to get the list of Humanized Immune-Checkpoint Mice models available
Humanized Cytokine Mice
Cytokines play a vital role in immune regulation and therapeutic intervention. Biocytogen offers a diverse range of mouse models featuring humanized cytokines and cytokine receptors, meticulously designed to mirror the complexities of human cytokine signaling. These models serve as invaluable tools for preclinical assessment, empowering researchers to explore innovative anti-human immunotherapies with confidence.
Click to get the list of Humanized Cytokine Mice models available.
Humanized GPCR Mice
G protein-coupled receptors (GPCRs) serve as vital channels for transmitting cellular growth and migration signals across various biological pathways. Given their involvement in immune regulation and cancer progression, GPCRs stand as promising targets for drug development. Yet, the intricate biochemical structure and shared homology among GPCR family members present challenges in targeting them effectively.
Biocytogen has engineered a range of humanized GPCR mouse models tailored specifically for testing human GPCR drug candidates. Our advanced models provide a unique opportunity for comprehensive evaluation, offering insights into safety, dosing, and efficacy of therapeutic candidates prior to clinical development.
Click to get the list of Humanized GPCR Mice models available.
